Cell Therapy and Cryopreservation
Standardize cell therapy discovery, development and manufacturing.
Standardize multiple points in the cell therapy workflow from cell preparation, to freezing, transport and thawing.
CoolCell® cell freezing containers provide demonstrated, controlled-rate freezing without the need for alcohol or expensive, dedicated equipment such as controlled-rate freezers. CoolCell cell freezing containers come in a range of sizes to fit both autologous and allogeneic therapies, and are adaptable for most cell types. There are several steps in the cell therapy process that may require cell freezing including generation of master cell bank, working cell bank and final cell therapy product.
Learn how to integrate CoolCell freezing containers into your process: GMP Cell Freezing Application.
TxCell integrates CoolCell into their Treg clinical trial
In a feasibility study for their Ovasave® clinical trials, France-based TxCell, SA determined CoolCell cell freezing containers performed equivalent to a controlled-rate freezer (CRF) for the development of of their cell therapy products. (Figure 1). Because CoolCell is adaptible to a GMP environment (Figure 2) considerably easier to deploy to clinical sites, is more cost-effective and requires no maintenance, it was adopted over a CRF for the Ovasave phase 2b trial. Learn how TxCell qualified and adopted CoolCell for their Treg clinical trial.
Cold Chain Management
Transport samples stored in liquid nitrogen
Liquid nitrogen-based CryoPod™ Carrier provides up to 4 hours of < -150°C temperature stability for valuable biological specimens and other materials. Ideal for transporting between buildings or around metro areas, the portable, compact carrier features an absorbent that prevents LN2 movement, minimizing risk of LN2 exposure to the specimens and operator. The electronic panel displays temperature, date and time and features audible and visual alarms, and logging capabilities. An optional automated filling station quickly and safely replenishes the 3L LN2 charge for extended operations.